Action-Man Colin Ross was dashing around the Province of Cheshire on Tuesday 11th October presenting cheques on behalf of the Cheshire Freemasons’ Charity to Four Charities but still found time to call on Lyn Edwards at the Foundation for Research into Prada-Willi Syndrome who’s Grandson has this disorder.
Lyn Edwards and Colin Ross at the Foundation for Research into Prada-Willi Syndrome
Prader-Willi syndrome (PWS) is a genetic disorder that occurs in approximately one out of every 15,000 births. PWS affects males and females with equal frequency and affects all races and ethnicities. PWS is recognized as the most common genetic cause of life-threatening childhood obesity.
PWS was first described by Swiss doctors Andrea Prader, Alexis Labhart, and Heinrich Willi in 1956 based on the clinical characteristics of nine children they examined. The common characteristics defined in the initial report included small hands and feet, abnormal growth and body composition (small stature, very low lean body mass, and early-onset childhood obesity), hypotonia (weak muscles) at birth, insatiable hunger, extreme obesity, and intellectual disability.
PWS results from an abnormality of chromosome 15, and definitive diagnosis is now based on genetic testing.